Vitiligo causes loss of skin pigment giving rise to white skin patches.
Vitiligo disease causes depigmentation of the skin in patches.
Autoimmunity causes vitiligo disorder
The most strong and accepted view about the causes of loss of pigmentation is autoimmunity.In an autoimmune disease an individual's immune system reacts and destroys his own organs and body tissues.
In vitiligo disorder, the immune system produces certain proteins known as cytokines (immunomodulating agents) which target and alter the pigment producing melanocytes and leads to their gradual death resulting in white skin patches.
There is another view that some autoimmune factor causes the self destruction of melanocytes and loss of pigment.
Persons already affected by other autoimmune disorders like psoriasis, rheumatoid arthritis and thyroid disease have the greater risk of loss of pigmentation.
The autoimmune disease of the adrenal glands (Addison's disease) has been associated with the occurrence of this disorder.
Thyroid disorder causes the disease with white patches having no pigment.
Inflammatory and autoimmune diseases of thyroid glands lead to their over expression or under expression.
Persons with this thyroid impairment have been found prone to loss of pigment.
There is a great possibility of children of the vitiligo affected parents developing this white patches.
It has been found that 30% of the persons affected by this disorder have at least one family member affected by the disorder of loss of skin pigment.
Individuals with vitiligo pigment disorder seem to inherit a batch of multiple genes which make them susceptible to loss of pigmentation.
Vitiligo affected hand
Physiological conditions and stress like sun burn and skin injury sometimes seem to be one of the causes for white patches.
Psychological stress triggers and leads to loss of pigment.
Environmental factors can also be the reason for white vitiligo patches.
There is another view that some autoimmune factor causes the self destruction of melanocytes and loss of pigment.
Persons already affected by other autoimmune disorders like psoriasis, rheumatoid arthritis and thyroid disease have the greater risk of loss of pigmentation.
The autoimmune disease of the adrenal glands (Addison's disease) has been associated with the occurrence of this disorder.
Thyroid disorder causes the disease with white patches having no pigment.
Inflammatory and autoimmune diseases of thyroid glands lead to their over expression or under expression.
Persons with this thyroid impairment have been found prone to loss of pigment.
Hereditary factors in loss of pigment
Strong evidence is pointing towards inheritance in persons whose close blood relatives already have this disorder.There is a great possibility of children of the vitiligo affected parents developing this white patches.
It has been found that 30% of the persons affected by this disorder have at least one family member affected by the disorder of loss of skin pigment.
Individuals with vitiligo pigment disorder seem to inherit a batch of multiple genes which make them susceptible to loss of pigmentation.
Psychological stress triggers and leads to loss of pigment.
Environmental factors can also be the reason for white vitiligo patches.
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