Showing posts with label patches. Show all posts
Showing posts with label patches. Show all posts

Monday, November 29

Black, dark discoloration of skin - Brown spots and patches

Black, dark brown skin discoloration spots and patches

Dark brown discoloration of skin and patches is due to hyperpigmentation.

Brown discoloration of skin and formation of pigmented patches in most of the cases is caused by excessive production of the melanin pigment.

Sun damage, diseases, inflammation, hormonal imbalances, injuries etc. can cause excess pigmentation leading to skin discoloration and the incidence of dark brown skin patches. People with dark skin tones as with Mediterranean, African or Asian origins are more prone for excess pigmentation.

Sun exposure

Sun exposure, which has ultraviolet A and ultraviolet B radiation, brings about color changes in two different ways. Initially the Ultraviolet A (UVA) radiation which is usually in the range of 320 to 400 nm., by oxidative stress, causes the release of melanin from the melanocytes and causes its oxidation by combining with oxygen leading to rapid darkening discoloration patches of melanin.

Secondly, melanogenesis, which is skin reaction to photo-damage from UV radiation (CPD-DNA damage or direct DNA damage), increases the production of melanin pigment. The tanning or darkening by melanogenesis is a delayed reaction and the brown patches become visible only about three days after exposure. Sunscreens, umbrellas and hats can go a long way in protection from sun damage.

Freckles, age or liver patches and lentigines

Freckles (aka ephelis) are brown discoloration often visible in people with fair complexion and are concentrated clusters of melanin deposits.
Though many people have freckles, their origin is genetic in nature and freckles are triggered by exposure to sun.

Freckles contrast from moles and lentigines in that there is no increase in the number of melanin producing cells. Lentigo (plural lentigines) is a benign hyperplasia (proliferation of cells) of melanocytes. Regardless of sun exposure lentigo is stable in color and differ from moles in its linear spread, whereas moles are multilayer nests of melanocytes.

Liver patches are associated with aging and are blemishes on the skin associated with exposure to UV radiation from the sun. These dark brown liver patches particularly form on the face, hands, neck, shoulders and head. Freckles, lentigines and liver patches are benign and harmless and if required can be treated with skin whitening treatments

Melasma - brown patches

Chloasma or melasma are dark hyperpigmentation patches particularly common in women. Melasma are irregular dark, brown patches of excess pigment found on the nose, upper cheek, lips and forehead causing cosmetic discoloration. Melasma is usually prevalent in pregnant women (mask of pregnancy), women using contraceptives or women under HRT (hormone replacement therapy) medications.

Melasma patches also prevalent in men and women of Jewish descent, Russian descent, German descent and Native American descent. Genetic predisposition, thyroid diseases and female hormones (estrogen and progesterone) are the determining factors of developing melasma.

Melanocytic nevus (mole) skin discoloration

Melanocytic nevus is a common dark brown growth of the epidermis which are known as birth mark. Melanocytic nevus may form subdermal under the skin or form a pigmented growth on the dermis. Melanocytic nevi present at the time of birth or around the time of birth are called congenital nevi.

Melanocytic nevi may also appear in the childhood or later stages of life and their discoloration may range fromlight to very dark brown. Though in most of the cases Melanocytic nevi are harmless, any mole which changes color, shape, size or hurts may have to be investigated as some can turn into melanoma (a type of skin cancer).

Addison's disease

Addison's disease, a chronic adrenal insufficiency disease, is a rare endocrine disorder wherein adrenal glands malfunction or show functional insufficiency. Apart from the symptoms like weight loss, weakness, nausea, fever, diarrhea, muscle pains and headache, the Addison's disease affected person suffers from dark brown skin discoloration patches. It can give rise to brown freckles on the face, neck and shoulders and also dark brown skin discoloration patches on the knees, elbows, toes, knuckles and forehead.

Alkaptonuria

Alkaptonuria or dark urine disease is a rare inherited disorder leading to degradation of tyrosine and production and accumulation of homogentisic acid. Alkaptonuria causes damage to cartilage and heart valves and precipitates formation of kidney stones. Alkaptonuria disorder leads to dark brown patches of skin in sun exposed areas and around sweat glands.

Acanthosis nigricans is brown to dark, velvety, poorly defined skin discoloration. Acanthosis nigricans dark brown skin discoloration patches usually found in the body folds like groins, armpits, neck folds etc. Acanthosis nigricans, typically occurs in persons below 40 years and it is associated with obesity, hormonal anamallies and insulin resistance. Control of blood sugar and obesity improves the symptoms.

Scleroderma diabeticorum and dark brown patches

Scleroderma diabeticorum is a rare disorder affecting people with type 2 diabetes. Scleroderma diabeticorum causes thickening of epidermis on the upper back and the back of the neck with excess of dark brown patches melanin deposits. Scleroderma diabeticorum can be treated by bringing blood sugar under control and using moisturizers for softening the epidermis.

Dark, brown skin discoloration between thighs and in armpits

In some persons, especially in obese persons, the skin between the thighs and also in the armpits gets dark brown discoloration patches due excess melanocyte deposit as a result of excessive sweating and dead cells build-up leading to dermatitis and related fungal infections. Use of antifungal preparations followed by exfoliation and dermabrasion, if necessary, can remove the excess skin pigmentation and the dark brown patches to a great extent.


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Wednesday, January 13

Causes of vitiligo skin disease - loss of skin pigment - white patches

White spots on skin, lips, fingernails, teeth, tonsils and genitalia > Vitiligo white skin patches > Causes > Signs > Diagnosis - Treatment and cure - Recent research

Vitiligo causes loss of skin pigment giving rise to white skin patches.
Vitiligo disease causes depigmentation of the skin in patches.
There are a number of possible causes for the onset of the disease. This disorder of white patches is believed to be primarily brought about by an autoimmune disease.

Autoimmunity causes vitiligo disorder

The most strong and accepted view about the causes of loss of pigmentation is autoimmunity.
In an autoimmune disease an individual's immune system reacts and destroys his own organs and body tissues.
In vitiligo disorder, the immune system produces certain proteins known as cytokines (immunomodulating agents) which target and alter the pigment producing melanocytes and leads to their gradual death resulting in white skin patches.
There is another view that some autoimmune factor causes the self destruction of melanocytes and loss of pigment.

Persons already affected by other autoimmune disorders like psoriasis, rheumatoid arthritis and thyroid disease have the greater risk of loss of pigmentation.
The autoimmune disease of the adrenal glands (Addison's disease) has been associated with the occurrence of this disorder.
Thyroid disorder causes the disease with white patches having no pigment.
Inflammatory and autoimmune diseases of thyroid glands lead to their over expression or under expression.

Persons with this thyroid impairment have been found prone to loss of pigment.

Hereditary factors in loss of pigment

Strong evidence is pointing towards inheritance in persons whose close blood relatives already have this disorder.
There is a great possibility of children of the vitiligo affected parents developing this white patches.
It has been found that 30% of the persons affected by this disorder have at least one family member affected by the disorder of loss of skin pigment.
Individuals with vitiligo pigment disorder seem to inherit a batch of multiple genes which make them susceptible to loss of pigmentation.
leucoderma
Vitiligo affected hand
Physiological conditions and stress like sun burn and skin injury sometimes seem to be one of the causes for white patches.
Psychological stress triggers and leads to loss of pigment.
Environmental factors can also be the reason for white vitiligo patches.

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Wednesday, January 6

Vitiligo - skin disease - depigmentation - white skin patches

White spots on skin, lips, fingernails, teeth, tonsils and genitalia > Vitiligo white skin patches > Causes > Signs > Diagnosis - Treatment and cure > Recent research

Vitiligo is a skin disorder or disease in which there is loss of skin pigment resulting in white depigmentation patches.

What is vitiligo (leucoderma or leukoderma)?

Our skin color is due to the melanin pigment present in it. The melanin pigment is produced by specialised cells in the epidermis called melanocytes. The melanin pigment is formed into bundles called melanosomes and deposited in the epidermis.
Due to some physiological conditions there is stoppage of pigment production or death and loss of the pigment producing cells in patches and white areas of depigmentation occur.
This condition of loss of pigmentation is called vitiligo (leucoderma or leukoderma).

Causes for vitiligo disorder

Though the basic cause of this disease is the depigmentation of the skin there are divergent views, theories and research results pointing to many possible factors like physiological conditions, hereditary disorders, genetic disorders, environmental factors, thyroid disorders, psychological stress and autoimmune diseases.
For more details about the causes read the page ' causes for vitiligo disorders'.

Who can be affected by this condition of depigmentation?

Worldwide it is estimated that this condition of loss of skin pigment is affecting 1-2% of the population.
This disease affects all races and both genders and appears prominent in dark skinned people.
Persons with autoimmune disease and thyroid disorder are prone to get vitiligo disorder.
The chances for the immediate relatives of an affected person to get this disorder are greater.

Patterns and types of vitiligo disease

Three types of this loss of skin pigmentation, namely focal, segmental and nonsegmental vitiligo are observed.
In the focal form of the disorder, the white patches are restricted to one or a few areas.
In non-segmented form the white patches appear on both sides and somewhat show symmetry.
These white patches of skin grow over a period of time to spread all over the body.
If the depigmentation is total or only a few pigment patches remain, the condition is called as vitiligo universalis.
Segmental vitiligo disease affects younger individuals. The disorder affects some parts of the body and may not appear in symmetry.

Diagnosis of white skin patches

Vitiligo disease appear as white skin patches around orifices of the body like mouth, nostrils, eyes etc. They also appear on the end of the limbs like fingers and toes.
These white patches are irregular in shape and keep growing in most of the affected persons. For more detail about diagnosis of the disorder read 'Diagnosis of vitiligo disease'.

Therapy and treatment for vitiligo skin disease

There is a difference between the approach towards this disorder between the western medicine and the oriental medicine.
In oriental medicine the claim is that it is addressing the underlying cause of the disease.
There are number of ways to alter the appearance in the vitiligo skin disease affected.
The white vitiligo disease patches can be hidden by application of camouflage creams and skin dyes.
Further treatment methods for the disease like topical application, oral medicine, phototherapy, surgical grafts, repigmentation and treatment with melanocyte cultures are possible.
For detail information on treatment of this disorder read the page "Therapy and treatment of vitiligo disease".

Psychological and aesthetic aspects of the disorder of loss of skin pigment

Though this disease has no harmful effects on the body, it devastates the mental health of the affected person leading him to mood and depression disorders.
The loss of aesthetic appearance and being stigmatised for the condition ruins the self-esteem and emotional health of the person affected by the disorder.
Those affected by this disease are tormented sub-consciously about others reactions, feel ashamed, embarrassed and dejected and may become introverts.

Support groups for the vitiligo disease affected

Considering the psychological impact of this disorder all over the world, a number of organisations have come up to help out the affected by educating them and providing them advice, counsel and course of treatment for the disease.
These efforts are to save the affected from becoming a burden on the society just because of this harmless skin condition.

Research on pigmentation, depigmentation and repigmentation of this skin disorder

Wide spread research is going on to tackle this disorder. Methods for repigmentation of these white skin patches are already known and further research is going on .
If the vitiligo disorder has affected more than 50% area, a process for depigmentation of the rest of the skin pigment is now known. Further research is being carried out in this aspect of tackling vitiligo disease.

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Monday, October 26

Pale white spots/patches on children skin face and body

White spots on the face of children

The cause of pale white spots and patches on the face and the body of children must be diagnosed and treated or else it may leave a psychological impact on the kids, apart from the physiological problems.

Various conditions and diseases can cause pale white spots/patches on the skin of children. Some are harmless and resolve by themselves. Many can cause health problems. It is very important for the parents to get the causes diagnosed and have the children treated if necessary.

Pale/white spots and patches arising out of injuries, burns and infections

These white spots are due to skin damage.
Repigmentation of these areas may take a long time or may not develop pigments fully.
These patches can be corrected by chemo or
.

Deficiency of vitamins (avitaminosis) causes pale white spots/patches on the skin

Vitamins are very essential components of our nutrition and the deficiency of them in children can cause many diseases and also affect their skin. Deficiency of B complex vitamins affect our skin in a number of ways.

The deficiency of Vitamin B12 causes pale white spots/patches on the skin especially on the forearms of the kids.These pale patches arise out of depigmentation of the skin and may later turn pink/red causing itching and distress to the kids. Giving food rich in vitamin B12 to the kids makes the pale white vitamin B12 deficiency spots/patches to disappear gradually.

Pale white spots and patches on the children caused by pityriasis alba

This is an asymptomatic condition, the cause of which is not known. The lesions initially appear slightly raised pinkish or reddish in color. Later they flatten out and turn pale white. This condition affects particularly children, more often boys. It usually affects the face of the child, especially cheeks, area around mouth and chin.

Pale white patches may also appear on shoulders arms and hands of kids. By puberty in most of the kids it resolves by itself. The condition may last to a few months or to years. may also recur. No specific treatment is required. Protective and preventive measures may be taken to avoid these pale white spots and patches on your children faces.

Milia (oil seeds or milk spots) causes small raised spots on the face, mouth roof and genitalia

Milia is quite often present in newborns and infants. These white may also affect older children and adults. Milia are keratin filled cysts and are benign and asymptomatic. Usually in newborns they disappear after a few weeks. In adults they may persist and can be removed by opening the cyst.

Fordyce pale white spots

These are usually found on the lips and genitalia. These white spots are actually sebaceous glands which do not have hair follicle association (ectopic sebaceous gland). These are harmless and of cosmetic worry only.

Pale patches caused by nevus depigmentosus

are hypopigmentation areas in the skin and may be present right from the birth. These pale spots are stable, harmless and non- contagious.

Pale white or brown patches/spots caused by tinea (pityriasis) versicolor

Skin yeast and M.globosa cause infections. This ailment usually affects teenagers and young adults. Kids are rarely affected. Malnourished children and kids with suppressed immunity are affected. The fungus can be treated with a number of anti-fungal topical and oral medications.

Pale white spots and patches caused by vitiligo (leucoderma)

is a skin disorder and gives rise to hypopigmentation of some areas of the skin. Autoimmunity is the main . In this ailment the immune cells kill the pigment producing cells (melanocytes) in some areas of the skin leading to white patches.

Pale white spots and patches of leprosy

Leprosy initially shows as pale white spots and patches on the skin, which are numb to touch. Though this is eradicated from most parts of the world, it is still persisting is some pockets of Africa and South east Asia. This is a curable bacterial disease. Areas of skin which lack sensation require immediate medical attention.
Sudden appearance of tender feeling to touch can be a hint of progressive damage to the peripheral nerves or even the spinal cord and the brain.

Pale white spots and patches arising on children must not neglected and immediate diagnosis and treatment must be given.

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Saturday, October 17

Causes of pityriasis alba-white/pale spots/patches on children

Pityriasis alba > Causes > Diagnosis > Treatment
A number of causes are related for the occurrence of pityriasis alba white/pale spots and patches on the face and body of children. But the knowledge of real reason is elusive.

Pityriasis alba is considered as an atopic dermatitis occurring in children, especially on their face, shoulders and arms and could be an independent eczema. The exact causes of these white spots is not known. The investigations of skin scrapings of a number of patients have indicated non involvement of bacteria and fungus.

Pityriasis alba is not contagious and has no definite etiologic agent. Studies have revealed that the hypopigmentation is due to reduction in the numbers of functional melanocytes and decrease of melanosomes in size and number. Dryness of skin, especially in winter appears to aggravate this ailment and increase the scale formation.

We can infer that cold dry condition may trigger and cause it in persons predisposed to it. In summer months, though the patches appear prominent due to tanning of the surrounding skin, there is no aggravation of the condition. Another hypothesis is that the deficiency of calcium and related vitamins precipitates this pityriasis ailment.

The explanation and reasoning is that pityriasis alba often occurs during the growing years of children. The growing children tend to get deficient in vitamins and calcium easily. Infestation with intestinal worms and parasites has been associated with pityriasis alba occurrence. In rural India deworming of the children is done by feeding them with a spoon of Castor oil with the belief that the condition will resolve.

Some theories have associated public swimming pools as one of the reasons of occurrence of pityriasis alba. Though the condition is asymptomatic for the affected child, it is of a big worry for the parents. Schools and daycare facilities will be very apprehensive about pityriasis alba and its causes and may insist on evaluation of the infective status of the condition.


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